Neopterin as an endogenous antioxidant
نویسندگان
چکیده
منابع مشابه
Neopterin acts as an endogenous cognitive enhancer
Neopterin is found at increased levels in biological fluids from individuals with inflammatory disorders. The biological role of this pteridine remains undefined; however, due to its capacity to increase hemeoxygenase-1 content, it has been proposed as a protective agent during cellular stress. Therefore, we investigated the effects of neopterin on motor, emotional and memory functions. To addr...
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ations of cell and organ function. Table 1 lists some of the better established examples in which radical species, such as the superoxide (O ) and hydroxyl (OH) radicals, and oxidants, such as singlet oxygen, hydrogen peroxide (H202), hypochiorous acid (HOCI), and aldehydes, are believed to play a causal role.’ In view of the general chemical reactivity of all these metabolic intermediates, a p...
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An enzyme-linked immunosorbent assay for neopterin using penicillinase as marker enzyme is reported here by polyclonal antibodies against neopterin conjugated to bovine serum albumin which were raised in rabbits. Immunoglobulin fractions were purified and coated on wells of microtiter plates. A chain heterology was introduced in neopterin derivative and conjugated to penicillinase. The assa...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1992
ISSN: 0014-5793
DOI: 10.1016/0014-5793(92)80610-s